Developmental Neurotoxicity Testing Research

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Bartmann, K., Bendt, F., Dönmez, A., Haag, D., Keßel, H.E., Masjosthusmann, S., Noel, C., Wu, J., Zhou, P., Fritsche, E. (2023). A human iPSC-based in vitro neural network formation assay to investigate neurodevelopmental toxicity of pesticides. ALTEX. 40(3), 452-470. doi: 10.14573/altex.2206031.

Hartmann, J., Henschel, N., Bartmann, K., Dönmez, A., Brockerhoff, G., Koch, K., Fritsche, E. (2023). Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays. Cells, 12(9), 1270. doi: 10.3390/cells12091270.

Klose, J., Pahl, M., Bartmann, K., Bendt, F., Blum, J., Dolde, X., Förster, N., Holzer, A.-K., Hübenthal, U., Keßel, H. E., Koch, K., Masjosthusmann, S., Schneider, S., Stürzl, L.-C., Woeste, S., Rossi, A., Covaci, A., Behl, M., Leist, M., Tigges, J., Fritsche, E. (2022). Neurodevelopmental toxicity assessment of flame retardants using a human DNT in vitro testing battery. Cell Biology and Toxicology, 38(5), 781–807. doi: 10.1007/s10565-021-09603-2.

Koch, K., Bartmann, K., Hartmann, J., Kapr, J., Klose, J., Kuchovská, E., Pahl, M., Schlüppmann, K., Zühr, E., & Fritsche, E. (2022). Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation. Frontiers in Toxicology, 4, 816370. doi: 10.3389/ftox.2022.816370.

Klose, J., Tigges, J., Masjosthusmann, S., Schmuck, K., Bendt, F., Hübenthal, U., Petzsch, P., Köhrer, K., Koch, K., & Fritsche, E. (2021). TBBPA targets converging key events of human oligodendrocyte
development resulting in two novel AOPs. ALTEX, 38(2), 215–234. doi: 10.14573/altex.2203151.

Tigges, J., Bielec, K., Brockerhoff, G., Hildebrandt, B., Hübenthal, U., Kapr, J., Koch, K., Teichweyde, N., Wieczorek, D., Rossi, A., & Fritsche, E. (2021). Academic application of Good Cell Culture Practice
for induced pluripotent stem cells. ALTEX, 38(4), 595–614. doi: 10.14573/altex.2101221.

Masjosthusmann, S., Blum, J., Bartmann, K., Dolde, X., Holzer, A. K., Stürzl, L. C., Keßel, H.E, Förster, N., Dönmez, A., Klose, J., Pahl, M., Waldmann, T., Bendt, F., Kisitu, J., Suciu, I., Hübenthal, U., Mosig, A., Leist, M., Fritsche, E. (2020). Establishment of an A Priori Protocol for the Implementation and Interpretation of an In-vitro Testing Battery for the Assessment of Developmental Neurotoxicity. EFSA Supporting Publications 17. doi:10.2903/sp.efsa.2020.en-1938.